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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:

期数:

2014年04期

页码:

262-264

栏目:

论著

出版日期:

2014-08-31

文章信息/Info

Title:

Clinical Analysis on 87 Patients with nonfunctional Pituitary Adenoma

作者:

邢德广;  陶钧;  丁大领;  王占福;  马二猛;  王军;  王运杰

山东大学第二医院

关键词:

无功能性垂体腺瘤; 临床治疗; 经鼻蝶显微手术

Keywords:

nonfunctional pituitary adenoma;  clinical treatment;  transsphenoidal microsurgery

分类号:

R738.6

文献标志码:

A

摘要:

目的：探讨无功能性垂体腺瘤的诊断治疗情况，提高对无功能性垂体腺瘤的认识。方法：回顾分析2009年1月至2012年1月本科收治的87例无功能性垂体腺瘤患者的临床资料。结果：根据临床表现，结合内分泌及影像学检查可对肿瘤明确诊断并选择最佳治疗方案。全部患者均经手术治疗，肿瘤全切除59例，次全切19例，大部分切除9例。术后视力、视野改善者43例，头痛缓解23例，无明显变化者20例，无手术死亡。术后平均随访6.5个月，其中实访82例，失访5例。结论：经鼻碟显微手术是目前治疗无功能性垂体腺瘤主要手术方法，手术成功率高。无功能性垂体腺瘤发病隐匿，容易延误诊治，影响手术疗效，早期诊断及治疗对患者术后症状的改善尤为重要。

Abstract:

Objective To investigate the diagnosis and treatment of nonfunctional pituitary adenoma and improve the understanding of nonfunctional pituitary adenoma. Methods Retrospectively analyzing the clinical information of 87 cases of nonfunctioning pituitary adenoma treated in our department since 2009 to 2012. Results Nonfunctional pituitary adenomas could be diagnosed, and provided the best therapeutic methods based on clinical manifestations, physical and endocrine examinations. All patients were treated by operation. Total resection was achieved in 59 cases, subtotal in 19 cases, partial in 9 cases. Vision improved in 43 patients, headache relieved in 23 cases, no significant changes in 20 cases, no death case. An average follow-up of 6.5 months, 5 patients were lost. Conclusion Transsphenoidal microsurgery is the main surgical method of nonfunctional pituitary adenomas, which has high success rate. Incidence of nonfunctional pituitary adenomas hide, diagnosis and treatment easily be delayed, leading to influence the surgical curative effect, so early diagnosis and treatment are particularly important in improving the postoperative symptoms.

备注/Memo

备注/Memo:

［收稿日期］ 2013-11-16 [基金项目] 国家自然科学基金

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更新日期/Last Update: 2014-08-15