[1]李彦东,更·党木仁加甫,麦麦提力·米吉提,等.后颅窝非囊结节型血管母细胞瘤的诊断及显微外科治疗[J].临床神经外科杂志,2018,15(05):367-371.[doi:10.3969/j.issn.1672-7770.2018.05.012]
 LI Yan-dong,Geng Dangmurenjiafu,Maimaitili Mijiti,et al.Diagnosis and microsurgical treatment of non-cystic nodular hemangioblastoma in posterior fossa[J].Journal of Clinical Neurosurgery,2018,15(05):367-371.[doi:10.3969/j.issn.1672-7770.2018.05.012]
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后颅窝非囊结节型血管母细胞瘤的诊断及显微外科治疗()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
15
期数:
2018年05期
页码:
367-371
栏目:
论著
出版日期:
2018-10-15

文章信息/Info

Title:
Diagnosis and microsurgical treatment of non-cystic nodular hemangioblastoma in posterior fossa
作者:
李彦东更·党木仁加甫麦麦提力·米吉提朱国华
830054 乌鲁木齐,新疆医科大学第一附属医院神经外科
Author(s):
LI Yan-dongGeng DangmurenjiafuMaimaitili Mijitiet al.
Department of Neurosurgery,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China
关键词:
血管母细胞瘤后颅窝显微外科手术
Keywords:
hemangioblastomaposterior fossamicrosurgery
分类号:
R739.41
DOI:
10.3969/j.issn.1672-7770.2018.05.012
文献标志码:
A
摘要:
目的 探讨后颅窝非囊结节型血管母细胞瘤的诊断、显微外科治疗及其并发症。方法 回顾分析2009年12月至2017年12月新疆医科大学第一附属医院神经外科收治,并行显微外科手术治疗的29例后颅窝非囊结节型血管母细胞瘤患者的临床资料,以及手术疗效、术后并发症。结果 本组患者中,男19例(65.5%),女10例(34.5%),男∶ 女为1.9∶ 1;多发年龄为35~55岁;病程10 d~6年,平均8.3个月。最多见的首发症状是头痛、头晕(86.2%)。28例患者肿瘤全切,1例患者次全切。术后9例患者(31.0%)出现并发症,其中感染发热7例(24.1%),脑脊液漏2例(6.9%)、面瘫1例(3.5%)、应激性消化道溃疡出血2例(6.9%)。术后通过门诊或电话随访患者28例,随访时间3个月~6年。术后6个月随访时,所有患者的KPS≥80分;1例术后面瘫患者,术后6个月时面瘫House-Brackmann分级标准达Ⅲ级;1例肿瘤次全切患者术后38个月时随访,残余肿瘤未见明显增大。结论 后颅窝非囊结节型血管母细胞瘤无特异性临床表现;头颅CT或MRI平扫+增强扫描是其主要诊断方法;显微外科手术切除是其首选治疗方法,手术全切肿瘤即可达到治愈。
Abstract:
Abstract:Objective To explore the diagnosis,microsurgical treatment and complications of posterior fossa non-nodular hemangioblastoma(HB).Methods The clinical data of 29 patients with posterior fossa non-cystic nodular HB were treated with microsurgery at the First Affiliated Hospital of Xinjiang Medical University from December 2009 to December 2017 were analyzed retrospectively.The clinical data,surgical efficacy and postoperative complications were also analyzed.Results Of 29 patients,there were 19 males (65.5%) and 10 females (34.5%).Male:female was 1.9:1.Tumor prone to age range from 35 to 55.The disease duration was 10 days to 6 years with an average of 8.3 months.The most common first symptoms were headache,dizziness (86.2%).28 cases were totally resected and one case was subtotal removed.9 patients (31.03%) had postoperative complications,postoperative infection fever in 7 (24.1%),cerebrospinal fluid leakage in 2 (6.9%),facial paralysis in 1(3.5%),and stress gastrointestinal ulcer bleeding in 2 cases.(6.9%).All 28 patients were followed up by outpatient or telephone and were followed up for 3 months to 6 years.At the 6-month follow-up,all patients had KPS ≥80 points.One patient had facial paralysis and the House-Brackmann grading standard was grade III at 6 months after operation.One case of subtotal tumor was followed up for 38 months.No significant increase was found in tumors.Conclusions The posterior cranial fossa non-cystic nodular HB has no specific clinical manifestations. CT or MRI plain scan+enhanced scan is the main diagnostic method.Microsurgical resection is the preferred method of treatment.Surgical complete resection can be achieved.

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更新日期/Last Update: 2018-10-10