[1]黄欢,茅帅东,李火平,等.颅内压/脑灌注压导向性治疗改善高级别破裂颅内动脉瘤预后的研究[J].临床神经外科杂志,2020,17(05):490-494.[doi:DOI:10.3969/j.issn.1672-7770.2020.05.003]
 HUANG Huan,MAO Shuai-dong,LI Huo-ping,et al.Evaluation of ICP/CPP guided treatment strategy in improving prognosis of poor-grade ruptured intracranial aneurysm[J].Journal of Clinical Neurosurgery,2020,17(05):490-494.[doi:DOI:10.3969/j.issn.1672-7770.2020.05.003]
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颅内压/脑灌注压导向性治疗改善高级别破裂颅内动脉瘤预后的研究()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
17
期数:
2020年05期
页码:
490-494
栏目:
动脉瘤专题
出版日期:
2020-10-13

文章信息/Info

Title:
Evaluation of ICP/CPP guided treatment strategy in improving prognosis of poor-grade ruptured intracranial aneurysm
文章编号:
202005003
作者:
黄欢茅帅东李火平尹建章陈婷张翔
202157 上海,上海市第十人民医院崇明分院神经外科(黄欢,茅帅东,李火平,尹建章,陈婷); 上海市第十人民医院神经外科(张翔)
Author(s):
HUANG Huan MAO Shuai-dong LI Huo-ping et al.
Department of Neurosurgery, Chongming Hospital Affiliated to Shanghai Tenth People’s Hospital, Shanghai 202157, China
关键词:
颅内压脑灌注压颅内破裂动脉瘤
Keywords:
intracranial pressure cerebral perfusion pressure ruptured intracranial aneurysm
分类号:
R739.41
DOI:
DOI:10.3969/j.issn.1672-7770.2020.05.003
文献标志码:
A
摘要:
目的研究颅内压/脑灌注压(ICP/CPP)导向性治疗策略对改善高级别破裂颅内动脉瘤远期预后的效果。方法回顾性分析48例高级别颅内破裂动脉瘤患者的临床资料。其中术后采用ICP/CPP导向性治疗的患者23例,采用常规治疗的患者25例;比较两组患者术后90 d的预后、迟发性脑梗死发生率、死亡率及并发症发生率。结果ICP/CPP导向性治疗组患者的迟发性脑梗死发生率明显低于常规治疗组,术后90 d时的预后良好率明显高于常规治疗组(均P<0.05)。而两组死亡率、并发症发生率间的差异均无统计学意义(均P>0.05)。结论在完善的神经重症支持下,ICP/CPP导向性治疗比常规治疗能明显降低高级别破裂颅内动脉瘤患者的迟发性脑梗死发生率,改善其远期预后。
Abstract:
Objective To investigate the effect of intracranial pressure/cerebral perfusion pressure(ICP/CPP)guided treatment strategy in improving the long-term prognosis of patients with poor-grade ruptured intracranial aneurysms. Methods The clinical data of 48 patients with poor-grade ruptured intracranial aneurysms were analyzed retrospectively, 23 of which underwent the ICP/CPP guided treatment and 25 cases underwent the conventional treatment. The prognosis at 90 days after the operation, the incidence of delayed cerebral infarction and complications, and mortality of the two groups were contrastively evaluated. Results Compared with the conventional treatment group, the ICP guided treatment group had lower incidence of delayed cerebral infarction and better prognosis in the 90 days follow-up. There was no significant difference in the mortality rate and the incidence of complications between the two groups(P>0.05). Conclusion Based on the support of comprehensive neuro intensive care, the ICP/CPP guided treatment strategy can significantly reduce the incidence of delayed cerebral infarction and improve the long-term prognosis of patients with poor-grade ruptured aneurysms, compared with the conventional treatment.

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更新日期/Last Update: 2020-10-16