[1]周勇智,邹元杰,刘永,等.三叉神经根入脑干区MRI形态学研究[J].临床神经外科杂志,2014,(01):29-32.
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三叉神经根入脑干区MRI形态学研究
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
期数:
2014年01期
页码:
29-32
栏目:
论著
出版日期:
2014-02-28

文章信息/Info

Title:
Morphological characteristics of trigeminal nerve root entry zone : an MRI study
作者:
周勇智;  邹元杰;  刘永;  刘宏毅;  刘文;  肖朝勇
南京脑科医院
关键词:
三叉神经痛; 磁共振成像; 形态学结构; 发病机制
Keywords:
trigeminal neuralgia;  magnetic resonance imaging;  morphological structure;  pathogenesis
分类号:
R745.1
文献标志码:
A
摘要:
目的 研究原发性三叉神经痛（TN）患者三叉神经根入脑干区（REZ）的形态结构及其临床应用价值。方法 36例TN患者和20例非TN患者作为健康对照纳入研究。所有受试对象采用3.0TMRI扫描，采用可变翻转角的三维快速自旋回波序列（3D-SPACE）分别扫描两侧REZ区的形态学结构。采取图像分析软件测量分析三叉神经脑池段长度、三叉神经脑桥角、桥小脑角池面积和三叉神经脑池段面积。结果 患侧三叉神经脑池段长度的均值、三叉神经脑桥角的均值、桥小脑角池面积的均值以及三叉神经脑池段面积的均值均小于健侧。对照组的三叉神经脑池段长度、三叉神经脑桥角、桥小脑角池面积及三叉神经脑池段面积的均值均大于疾病组。结论 三叉神经脑池段较短，三叉神经脑桥角锐利，易发生神经血管冲突，临床上易导致TN；MRI形态学信息有利于疾病的诊断及手术决策的选择。
Abstract:
Objective To evaluate the morphological structures of the trigeminal nerve root entry zone (REZ) in patients with trigeminal neuralgia（TN） and their clinical values. Methods Thirty-six patients with TN and twenty healthy controls were enrolled. All the subjects were scanned by high-resolution 3.0T MRI. 3D sampling perfection with application optimized contrasts using different flip angle evolutions (3D-SPACE) was used to measure bilaterally morphological structures of REZ. Results The mean length of the cisternal segment of the trigeminal nerve， the trigeminal-pontine angle， the cross-sectional area of the cerebellopontine angle (CPA) cistern and the cross-sectional area of the cisternal segment of the trigeminal nerve on the symptomatic side were smaller than that on the asymptomatic side. And all the above morphological parameters tended to be larger in controls than in patients. Conclusions Shorter cisternal trigeminal nerve and sharper trigeminal-pontine angle increase the chance of neurovascular conflict (NVC) ， and are more likely to cause TN . The smaller area of the cisternal segment of trigeminal nerve is indicative of trigeminal nerve atrophy resulted from long-term compression. These parameters can be used for diagnostic indicators of TN and surgical decision-making.

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备注/Memo

备注/Memo:
［收稿日期］ 2013-12-02
更新日期/Last Update: 2014-02-15