[1]马俊伟,蒋栋毅,陈寒春,等.神经内镜下经鼻蝶入路垂体腺瘤手术切除的临床疗效分析[J].临床神经外科杂志,2015,(01):48-50.
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神经内镜下经鼻蝶入路垂体腺瘤手术切除的临床疗效分析()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
期数:
2015年01期
页码:
48-50
栏目:
论著
出版日期:
2015-02-15

文章信息/Info

Title:
Analysis of clinical efficacy of endoscopic endonasal transsphenoidaloperation for pituitary adenoma
作者:
马俊伟 蒋栋毅 陈寒春 周强 杨德宝 沈李逵 费喜峰 向海涛
北京军区总医院附属八一脑科医院
关键词:
神经内镜垂体肿瘤手术并发症经鼻蝶入路
Keywords:
Neuroendoscope Pituitary neoplasms Operation Complication Transsphenoidal surgery
分类号:
R736.4
文献标志码:
A
摘要:
目的:探讨神经内镜下经鼻蝶入路垂体腺瘤手术切除的临床治疗效果。 方法:回顾分析上海交通大学医学院附属苏州九龙医院神经外科2011年7月至2013年8月收治的神经内镜下经鼻蝶入路垂体腺瘤手术切除的患者共98例,其病理结果均为垂体腺瘤。手术前后分别行内分泌学检查,术后随访3月复查垂体MRI。 结果:肿瘤全切除率78.6%(77例),次全切除率16.3%(16例),部分切除率5.1%(5例)。术后视力、视野较术前明显改善者18例,激素水平较术前下降或完全恢复至正常者35例,脑脊液漏6例,其中4例经腰大池置管后治愈,另外2例行脑脊液鼻漏修补手术治愈,暂时性尿崩5例,高热及电解质紊乱2例,无死亡病例。术后平均住院时间5.5天。 结论:神经内镜下经鼻蝶入路切除垂体腺瘤是一种安全、微创、有效的治疗方式,术后并发症低,减轻患者痛苦,缩短病人住院时间。
Abstract:
Objective To analyze the clinical effect of endoscopic transsphenoidal pituitary adenoma resection. Methods Retrospective analysis of 98 patients in Suzhou Kowloon Hospital Affiliated Shanghai Jiaotong University from July 2011 to August 2013, who were operated transsphenoidal by endoscopy, the pathology results were pituitary adenoma. Endocrinology examination were performed before and after surgery, patients were followed up to review the pituitary MRI 3 months after operation. Results: The tumor resection rate was 78.6% ( 77 cases ) , subtotal resection rate of 16.3% ( 16 cases ) , partial resection rate of 5.1% ( 5 cases ) . Visual acuity, field of vision before surgery significantly improved in18 cases , compared with the preoperative hormone levels decrease or completely restored to normal in 35 cases , six cases of cerebrospinal fluid leakage , including four cases after lumbar catheter cure , another 2 cases of cerebrospinal fluid rhinorrhea repair surgery cured, 5 cases of transient diabetes insipidus, 2 cases of fever and electrolyte imbalance but no death. The mean postoperative hospital stay was 5.5 days. Conclusions: Endoscopic transsphenoidal pituitary adenoma resection is safe, minimally invasive and effective, postoperative complications is low, and it can relieve pain and shorten hospital stay.

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备注/Memo

备注/Memo:
[收稿日期] 2014-06-19 [基金项目] 国家自然科学基金
更新日期/Last Update: 2015-02-15