脑磁图静息态脑网络定位与皮质脑电图的对照研究-《临床神经外科杂志》

文章信息/Info

Title:: A comparative study between magnetoencephalography resting-state neural networks and electrocorticography locating

Keywords:: Magnetoencephalography; resting-state neural networks; epilepsy; surgery

摘要:: 目的对照脑磁图静息态脑网络定位与皮质脑电图的一致性。方法选取难治性癫痫患者16例，术前均运用脑磁图静息态网络定位，同时运用传统的脑磁图dipole法和SAM法皮质脑电图定位，与皮质脑电图的结果对照，分别比较两种技术的吻合度。结果 16例患者均有明显的棘波放电，dipole定位局限10例，散发6例，SAM值升高单病灶11例，多病灶5例。16人均显示静息态脑网络异常，敏感度100% (16/16)。dipole定位ECoG的定位符合率为62.5%（10/16），SAM与ECoG的定位符合率为68.7%（11/16），MEG脑网络功能异常与ECoG的定侧符合率为100%，定位符合率为81.2%(13/16)。结论：磁图静息态网络定位可以敏感地定位癫痫放电区，可以为癫痫手术规划提供帮助。

Abstract:: Purpose: The present study aims to contrast the consistency of magnetoencephalography resting-state neural networks and electrocorticography locating. Method: 16 refractory epilepsy patients were recruited. Magnetoencephalography resting-state neural networks and electrocorticography were located before surgical operation to contrast the consistency. Result: Spikes were observed in 16 patients, and located focally in 10 patients and sporadically 6 patients by dipole. Single focus in 11 patients and multiple lesions in 5 patients were located by SAM. The resting state brain network of all patients were abnormal, the sensitivity was 100%(16/16). The coincidence rate was 62.5% (10/16) between Dipole and ECoG, 68.7% (10/16) between SAM and ECoG, 81.2%(13/16) between MEG and ECoG locating seizure onset zones, 100% between MEG and ECoG locating resting state brain network. Conclusion: Magnetoencephalography resting-state neural networks may locate locate seizure onset zones, and contribute epilepsy operation.