[1]孟大伟,石林,刘焕光.颞叶癫痫患者手术后早期发作对远期疗效的影响[J].临床神经外科杂志,2015,(03):185-188.
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颞叶癫痫患者手术后早期发作对远期疗效的影响()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
期数:
2015年03期
页码:
185-188
栏目:
癫痫专题 论著
出版日期:
2015-06-15

文章信息/Info

Title:
Acute postoperative seizures and long-term seizure outcome after surgery for temporal lobe epilepsy
作者:
孟大伟 石林 刘焕光
首都医科大学附属北京天坛医院神经外科
关键词:
颞叶癫痫术后早期发作影响因素预后
Keywords:
Temporal lobe epilepsyAcute postoperative seizuresinfluencing factorsprognosis
分类号:
R742.1
文献标志码:
A
摘要:
目的探讨颞叶癫痫患者手术后早期发作的影响因素及其对预后的影响。方法回顾性分析2011年2月至2012年10月我院收治的行手术治疗的96例颞叶癫痫患者的临床资料,并进行随访,分析癫痫手术后早期发作的影响因素及其对长期预后的影响。结果术后随访所有患者EngelⅠ级73例,EngelⅡ级11例,EngelⅢ级9例,EngelⅣ级3例。15例患者术后出现APOS,随访EngelⅠ级8例,EngelⅡ级3例,EngelⅢ级3例,EngelⅣ级1例。患者的年龄、性别、病程、术前发作频率、发作类型、MRI表现、切除侧别、术后病理等对术后早期发作无影响。出现术后早期发作的患者的癫痫缓解率明显低于无术后早期发作的患者(P<0.05),惯常发作的患者的癫痫缓解率明显低于非惯常发作的患者(P<0.05)。结论颞叶癫痫患者术后早期发作的出现提示预后不良,发作形式表现为惯常发作的患者更容易出现癫痫复发。
Abstract:
Objective To investigate the factors associated with acute postoperative seizures after temporal lobe epilepsy surgery and the prognostic significance of acute postoperative seizures in temporal lobe epilepsy surgery. Methods Between February 2011 and October 2012, clinical data of 96 temporal lobe epilepsy patients were collected in our hospital. The factors associated with acute postoperative seizures after temporal lobe epilepsy surgery and the prognostic significance of acute postoperative seizures were analyzed. Results The following up showed that according to Engel classification, gradeⅠwas 73 cases, grade Ⅱ 11 cases, grade Ⅲ 9 cases and grade Ⅳ 3 cases. 15 patients had acute postoperative seizures, according to Engel classification, gradeⅠwas 8cases, grade Ⅱ 3cases, grade Ⅲ3cases and grade Ⅳ 1 cases. The factors such as age at onset, gender, duration of seizures, seizure frequency, seizure types, MRI manifestation, side of resection, pathology had no effect on the occurrence of acute postoperative seizures. Patients with acute postoperative seizures had wores prognosis compared with patients without acute postoperative seizures(P <0.05). Patients who had acute postoperative seizures similar to preoperative habitual seizures were less likely to have an excellent outcome than patients without acute postoperative seizures(P<0.05). Conclusion Acute postoperative seizures after temporal lobe epilepsy surgery predicts bad prognosis. Patients who had acute postoperative seizures similar to preoperative habitual seizures were less likely to have seizure recurrence.

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备注/Memo

备注/Memo:
[收稿日期] 2015-03-31 [基金项目]国家自然科学基金(81171217)
更新日期/Last Update: 2015-06-15