[1]张光明,韩宏彦,徐金山.涉及中央前回的顽固性癫痫外科治疗[J].临床神经外科杂志,2015,(03):189-191.
点击复制

涉及中央前回的顽固性癫痫外科治疗()
分享到:

《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
期数:
2015年03期
页码:
189-191
栏目:
癫痫专题 论著
出版日期:
2015-06-15

文章信息/Info

Title:
Surgical Treatment for Refractory Epilepsy Related to Precentral Gyrus
作者:
张光明 韩宏彦 徐金山
中国医科大学航空总医院神经外科癫痫中心
关键词:
中央前回运动功能区癫痫疗效偏瘫
Keywords:
Epileptogenic resection Primary motor area Epilepsy Curative effect Hemiplegia
分类号:
R742.1
文献标志码:
A
摘要:
目的 探索涉及中央前回的顽固性癫痫的外科治疗效果。方法 癫痫发作起始位于或邻近中央前回的顽固性癫痫患者,开颅结合立体定向方法置入栅格状和深部电极。根据发作期颅内脑电图,电刺激,皮层诱发电位和高频颅内脑电图功能定位结果确定中央前回和致痫灶,镜下切除致痫灶。随访1年并回顾性分析23例患者致痫灶切除术后效果。结果 癫痫治疗效果:Engel I级 19例;Engel II级 3例;Engel III-IV级 1例。所有患者致痫灶切除术后第一天均出现单侧或单个肢体偏瘫,术后1年15例患者肌力恢复4级以上,无明显功能功能障碍,8例患者肌力3级及以下,遗留功能障碍。结论 涉及中央前回的顽固性癫痫致痫灶切除术后多数患者可获得癫痫治愈而不遗留明显功能障碍。
Abstract:
Objective To explore the outcomes of epileptogenic zone resection of refractory epilepsy originating from areas related to precentral gyrus. Methods Patients with refractory epilepsy originating from areas related to precentral gyrus underwent intracranial electrodes implantation. Grid and depth electrodes were implanted through craniotomy associated by stereotactic technique. Precentral gyrus and epileptogenic zone resection were detected by intracranial EEG, electric stimulation, cortical evoked potentials and high frequency oscillation. Epileptogenic zone was resected under microscope. Results The outcome of epilepsy was Engel I in 19 cases, Engel II in 3 cases and Engel III in 1 case. All patients experienced unilateral or single limb hemiplegia on first postoperative day. 15 cases, with muscle strength over grade 4, had no obvious dysfunction at 1 year after operation and 8 cases, with muscle strength grade 3 or lower, had dysfucntion. Conclusion Most patients of refractory epilepsy originating from areas related to precentral gyrus were seizure free and had no obvious dysfunction after epileptogenic zone resection.

备注/Memo

备注/Memo:
[收稿日期] 2015-03-31 [基金项目]国家自然科学基金面上项目
更新日期/Last Update: 2015-06-15