[1]王圆庆,姚一,江建东,等.大脑半球切除术治疗2例4月龄症状性West综合征报告及文献复习[J].临床神经外科杂志,2015,(03):205-208.
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大脑半球切除术治疗2例4月龄症状性West综合征报告及文献复习()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
期数:
2015年03期
页码:
205-208
栏目:
癫痫专题 论著
出版日期:
2015-06-15

文章信息/Info

Title:
Report and review of the literature of hemispherectomy on two cases of symptomatic West syndrome
作者:
王圆庆 姚一 江建东 张小斌
解放军第一七四医院暨厦门大学附属成功医院神经医学中心
关键词:
婴儿癫痫West综合征手术
Keywords:
InfantepilepsyWest syndromesurgery
分类号:
R742.1
文献标志码:
A
摘要:
目的:对2例4月龄症状性West综合征实施大脑半球切除术后随访,并结合文献分析大脑半球切除术后癫痫控制效果及神经功能恢复状况。方法:2例4月龄患儿均为一侧半球广泛病变,具有典型West综合征临床特点,进行相关检查及详细术前评估后,在导航系统引导下行功能性大脑半球切除术治疗。结果:手术过程顺利,术后2例患者发作消失,术后随访31个月、28个月,无癫痫发作,2例肢体运动改善,1例遗留轻度肢体偏瘫,智力及认知功能明显改善,复查脑电图均未见高幅失律。结论:结合文献复习,对于半球病变导致的West综合征早期行手术治疗可获得满意的效果。术后不仅癫痫发作可以完全消失,而且患儿的运动、智力和认知功能在不同程度上都有所提高,生活质量明显改善。
Abstract:
Objective 2 cases of symptomatic West syndrome 4 months follow-up after implementing hemispherectomy, analysis control effect and the status of the neural function recovery combined with literature after hemispherectomy epilepsy. Methods Two cases of four-month-old infants are side hemisphere extensive lesions, with typical clinical features of West syndrome. After the relevant examination and detailed preoperative assessment, the navigation system guided functional hemispherectomy treatment. Results The surgery went smoothly , seizures disappeared after two patients were followed up for 31 months, 28 months, seizure relief, two cases of limb movement improved, one case of mild left hemiplegia,intellectual and cognitive function improved significantly , review the EEG showed no hypsarrhythmia . Conclusion The combination of literature review , for West syndrome early surgical treatment of focal brain structure abnormalities caused obtain satisfactory results. Postoperative seizures can not completely disappeared, but the movement of children, intelligence and cognitive function improved in varying degrees, have the quality of life improved significantly.

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备注/Memo

备注/Memo:
[收稿日期] 2015-03-31 [基金项目]厦门市科技计划指导性项目2011S0461
更新日期/Last Update: 2015-06-15