[1]李煜环,孙永锋,翟卫东,等.伴海马硬化的颞叶内侧面癫痫手术治疗临床分析[J].临床神经外科杂志,2015,(06):438-441.
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伴海马硬化的颞叶内侧面癫痫手术治疗临床分析
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
期数:
2015年06期
页码:
438-441
栏目:
论著
出版日期:
2015-12-15

文章信息/Info

Title:
Clinical features and surgical treatment of temporal lobe epilepsy in patients with hippocampal sclerosis
作者:
李煜环 孙永锋翟卫东 袁俊
武警北京市总队医院
关键词:
颞叶癫痫海马硬化手术临床分析
Keywords:
Temporal lobe epilepsy Hippocampal sclerosis Surgeryclinical analysis
分类号:
R742.1
文献标志码:
A
摘要:
目的 探讨伴海马硬化的颞叶内侧面癫痫患者的临床特点以及手术治疗的疗效。 方法回顾性分析我院2010年5月至2014年7月间诊治的47例伴海马硬化的颞叶内侧面癫痫患者,其中癫痫全身强直-痉挛性发作17例,部分性发作继发全身性发作8例,复杂部分性发作22例,结合视频脑电图检查结果、MRI以及临床表现,对其行标准前颞叶切除术。结果 术后病理诊断均为海马硬化,所有患者均未出现永久性神经功能障碍,无重大并发症,术后Engel分级结果:I级,占76.6%;II级,占10.6%;III级,占8.5%;IV,占4.3%。结论:对于明确诊断颞叶癫痫伴有海马硬化的患者,标准前颞叶切除术(包括大部分海马和杏仁核)疗效满意,临床应在规范操作的基础上,推广应用此方法。
Abstract:
Objective To discuss the clinical features of temporal lobe epilepsy in the patients with hippocampal sclerosis and curative effects of surgery on it. Methods Retrospective analysis 47 cases of intractable temporal lobe epilepsy patients diagnosed and treated in our hospital from In May 2010 to July 2014, The clinical manifestations included generalized tonoclonic seizure in 17 cases,generalized seizure secondary to partial seizure in 8,and complex partial seizure in 22. After the examination of Video EEG (V-EEG) and MRI,we performed the standard anterior temporal lobe resection treatment in the 47 cases.Results The hippocampal sclerosis was confirmed by the postoperative pathological examination. All patients had no permanent neurological deficits and significant postoperative complications. Engel classification results after operation: class I (76.6%), grade II (10.6%), grade III accounted for 8.5%; Level IV (4.3%).Conclusions The operative efficacy of temporal lobe epilepsy with hippocampal sclerosis is satisfied. The standard anterior temporal lobe resection treatment is worthy of promotion and application for the future on the basis of the standardized operation.

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备注/Memo

备注/Memo:
[收稿日期] 2015-05-12 [基金项目]国家自然科学基金
更新日期/Last Update: 2015-12-15