[1]周平,邓燕,王辉,等.磁共振灌注成像在联合血管重建术治疗烟雾病中的应用[J].临床神经外科杂志,2016,(03):197-200.
 ZHOU Ping,DENG Yan,WANG Hui,et al.The value of MR perfusion imaging in treatment of moyamoya disease treated by combined revascularization[J].Journal of Clinical Neurosurgery,2016,(03):197-200.
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磁共振灌注成像在联合血管重建术治疗烟雾病中的应用()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
期数:
2016年03期
页码:
197-200
栏目:
论著
出版日期:
2016-06-10

文章信息/Info

Title:
The value of MR perfusion imaging in treatment of moyamoya disease treated by combined revascularization
作者:
周平邓燕王辉汪超甲刘开军李安荣周一陈劲草
445000十堰市太和医院(湖北医药学院附属医院)神经外科(周平,王辉,邓燕,汪超甲,刘开军,李安荣,周一);武汉大学附属中南医院神经外科(陈劲草)
Author(s):
ZHOU PingDENG YanWANG Huiet al
Department of Neurosurgery,Shiyan Taihe Hospital(Hospital Affiliated Hubei University of Medicine),Shiyan 445000,China
关键词:
烟雾病血管重建磁共振灌注成像
Keywords:
moyamoya diseaserevascularizationMR perfusion imaging
文献标志码:
A
摘要:
目的:探讨磁共振(MR)灌注成像在烟雾病联合血管重建术治疗中的应用价值。方法:回顾性分析21例采用颞浅动脉大脑中动脉搭桥+颞肌贴附术治疗的烟雾病患者的MR灌注成像资料。将术前、术后1周和术后3个月的MR灌注成像数据相对脑血容积(rCBV)、相对脑血流量(rCBF)和相对平均通过时间(rMTT)值进行收集、整理后进行统计学分析。结果:所有患者术前MR灌注成像表现为额叶、颞叶不同程度低灌注,术后1周发现术侧额颞部灌注较术前有所好转,术后3个月改善更为明显。将各参数均值分别行方差分析,将方差分析差异有统计学意义的变量进一步进行LSD-t检验,发现术前与术后1周额颞叶rCBF、MTT的差异无统计学意义(均P>0.05),与术后3个月相比差异有统计学意义(均P<0.05);术后1周及术后3个月与术前枕叶rCBV相比差异有统计学意义(P<0.05)。结论:MR灌注成像技术能够有效评估联合血管重建术前后患者脑血流动力学的改变,因此能有效评估其治疗效果。
Abstract:
Abstract:Objective:To study the value of magnetic resonance perfusion imaging in the treatment of moyamoya disease.Methods:The MR perfusion imaging data of 24 cases of moyamoya disease treated by superficial temporal artery-middle cerebral artery bypass+temporalis muscle attachment(STA-MCA bypass+EMS) were analyzed retrospectively.The value of relative cerebral blood flow(rCBF),relative cerebral blood volume(rCBV),relative mean transit time(MTT) before the operation,after 1 week and after 3 months,were collected and compared.Results:The MRI perfusion imagine of all patients before the operation showed that frontal and temporal lobe hypo perfusion in varying degrees.We found that perfusion of the frontotemporal lobe of the operative sides improving after 1 week,but more obviously after 3 months.Each parameter mean variance analysis were performed.The variable analysis of variance was significant,further LSDtest showed that there were no significant difference between the MTT of frontal lobes before and 1 week after operation(P>0.05) and that there was no significant difference between the rCBV of frontal lobes before and 1 week after the operation(P>0.05),while compared with which 3 months after operation there were significant between them(all P<0.05).There was significant differences of occipital lobe rBV before and after sugery,but no significance compaired 1 week with 3 months after operation(P>0.05).Conclusions:MR resonance perfusion imaging could demonstrate the cerebral hemodynamic changes in patients before and after surgery,it could assess the treatment effectively.

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更新日期/Last Update: 2016-06-15