[1]王天伟,牛小东,毛庆.《艾滋病合并胶质瘤2例报告及文献复习》[J].临床神经外科杂志,2017,14(02):91-94.
 WANG Tian-wei,NIU Xiao-dong,MAO Qing..Glioblastoma in patient with AIDS:two cases report and review of literatures[J].Journal of Clinical Neurosurgery,2017,14(02):91-94.
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《艾滋病合并胶质瘤2例报告及文献复习》()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
14
期数:
2017年02期
页码:
91-94
栏目:
胶质瘤专题
出版日期:
2017-04-10

文章信息/Info

Title:
Glioblastoma in patient with AIDS:two cases report and review of literatures
作者:
王天伟牛小东毛庆
610041 成都,四川大学华西医院神经外科
Author(s):
WANG Tian-weiNIU Xiao-dongMAO Qing.
Department of Neurosurgery,West China Hospital,Sichuan University,Chengdu 610041,China
关键词:
胶质瘤胶质母细胞瘤AIDSHIV肿瘤治疗电场
Keywords:
gliomaglioblastomaAIDSHIVTTF
分类号:
R739.41
文献标志码:
A
摘要:
目的:探讨艾滋病(AIDS)合并胶质瘤的临床特点、诊疗方案及可能的相关因素。方法:回顾性分析2例AIDS合并胶质瘤患者的临床资料;并结合数据库检索相关文献,多因素分析不同因素对患者生存时间的影响。结果:检索到31篇文献,符合标准的病例共35例。分析结果显示,不同诊疗方式患者的生存时间的差异有统计学意义(P=0.006);而年龄、性别、肿瘤部位及级别的不同对患者生存期的影响无统计学意义(均P>0.05)。结论:对于AIDS合并胶质瘤患者,手术后放、化疗比活检后放、化疗更有助于延长其生存期。
Abstract:
Objection: To explore the therapeutic schedule for acquired immunodeficiency syndrome(AIDS) patients with glioma.Two case reports will be described and published literature before will be discussed in this study.Methods:We performed a quantitative and comprehensive systematic literature review of AIDS patient with glioma.Then using those cases conformed to inclusion criteria to make a statistical analysis to discuss different treatment,sex,grade,and location whether can influence the patients’ lifetime respectively.Result:We evaluated 59 patients from 31 studies,finally 35 caseswere included our study depending on the inclusion criteria.Most of patients accepted radiotherapy (RT) and /or chemotherapy(CT) after resection or biopsy.We had carried out a survival analysis for the HIV patients suffered from glioma by different ways of diagnosis and treatment.The P value is 0.006.The outcome has statistical significance.As for other factors,the P>0.05,having no statistical significance.Conclusion:As for those patients,surgical resection combined RT and/or CT is more contributing to extent the patients’ median survival time and improve the quality of life than biopsy.However,the relationship between other factors and lifetime have no statistical significance.

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备注/Memo

备注/Memo:
四川省科技支撑计划项目( 2016TJPT0012)
更新日期/Last Update: 2017-02-10