[1]王金龙,刘亚军,罗坤,等.脊柱旁与椎管内节细胞神经瘤的临床诊断及外科手术治疗[J].临床神经外科杂志,2017,14(05):356-365.
 WANG Jin-long,LIU Ya-jun,LUO Kun,et al.Clinical diagnosis and surgical treatment of paravertebral and spinal ganglioneuroma[J].Journal of Clinical Neurosurgery,2017,14(05):356-365.
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脊柱旁与椎管内节细胞神经瘤的临床诊断及外科手术治疗()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
14
期数:
2017年05期
页码:
356-365
栏目:
论著
出版日期:
2017-10-23

文章信息/Info

Title:
Clinical diagnosis and surgical treatment of paravertebral and spinal ganglioneuroma
作者:
王金龙刘亚军罗坤郭运发吴昊通讯作者:罗坤
830054 乌鲁木齐,新疆医科大学第一附属医院神经外科中心
Author(s):
WANG Jin-longLIU Ya-junLUO Kunet al.
Department of Neurosurgery,the First Affiliated Hosipital of Xinjiang Medical University
关键词:
节细胞神经瘤诊断手术治疗疗效
Keywords:
ganglioneuromadiagnosissurgical treatmentcurative effects
分类号:
R730.264
文献标志码:
A
摘要:
目的:探讨脊柱旁与椎管内节细胞神经瘤的临床诊断及外科手术治疗。方法:回顾性分析15例脊柱旁与椎管内节细胞神经瘤手术治疗患者的临床资料。15例患者术前均行CT检查,其中2例椎管内病变患者同时行MRI检查。行神经显微手术患者2例,行腔镜手术3例,其余10例患者行开放性手术。结果:本组患者中,2例患者术前依据影像学检查明确诊断为节细胞神经瘤,其他13例患者术后经病理学检查确诊。术后病理诊断均为节细胞神经瘤,其中A型13例、B型0例、C型2例。肿瘤次全切除者9例,全切除者6例;术后均未行放化疗。2例全切除患者术后出现严重并发症。随访2~47.8个月,平均(25.96±4.08)个月,15例患者均无肿瘤复发及转移。结论:节细胞神经瘤早期无任何特异性临床表现,实验室检查无异常,影像学检查可辅助诊断,最终确诊要依靠病理学检查。节细胞神经瘤手术治疗(全切或次全切除)的效果较好,患者大多预后良好。
Abstract:
Objective:To investigate the clinical diagnosis and surgical treatment of paravertebral and spinal ganglioneuroma. Methods:Clinical data of 15 patients with paravertebral and spinal ganglioneuroma were analyzed retrospectively.15 patients were performed CT scanning,MR imaging was obtained in 2 patients.All 15 patients underwent surgical treatment,including 2 microsurgery treatments,3 endoscopic surgeries and the others with open surgeries. Results:Of 15 patients,2 were diagnosed as ganglioneuroma by the imaging data before operation,while the other cases were diagnosed by pathology.After operation,the pathological diagnosis showed 13 cases of ganglioneuroma(type A) and 2 ganglioneuroblastoma (type C).Subtotal removal was achieved in 9 patients and total removal in 6.2 cases of total resection occurred severe postoperative complications.None of them received radiotherapy and chemotherapy after operation,all patients were followed up for 2 to 47.8 months(25.96±4.08months),no recurrance or metastasis occurring after surgery. Conclusions:Mostly ganglioneuroma in its early stage had no specific clinical manifestation,the laboratory examination is normal,and imaging examination could promote the diagnosis,while the confirmed diagnosis depends on pathological examination.GN is generally considered a benign tumor and aggressive surgical approach should not be recommended.The prognosis of incomplete resection is mostly good.

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备注/Memo

备注/Memo:
国家自然科学基金(81660471)
更新日期/Last Update: 2017-10-10