[1]惠卫宁,邵国平,黄炜,等.神经内镜下垂体腺瘤假包膜切除的临床、病理研究[J].临床神经外科杂志,2018,15(04):308-311.
 HUI Wei-ning,SHAO Guo-ping,HUANG Wei,et al.Clinical and pathological study on resection of pseudocapsule of pituitary adenoma by neuroendoscopy[J].Journal of Clinical Neurosurgery,2018,15(04):308-311.
点击复制

神经内镜下垂体腺瘤假包膜切除的临床、病理研究()
分享到:

《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
15
期数:
2018年04期
页码:
308-311
栏目:
临床研究
出版日期:
2018-08-15

文章信息/Info

Title:
Clinical and pathological study on resection of pseudocapsule of pituitary adenoma by neuroendoscopy
作者:
惠卫宁邵国平黄炜褚荣涛魏炜李向东惠国桢
215500 常熟,常熟市第二人民医院神经外科(惠卫宁,邵国平,黄炜,褚荣涛),病理科(魏炜);苏州大学附属第一医院神经外科(李向东,惠国桢)
Author(s):
HUI Wei-ningSHAO Guo-pingHUANG Weiet al.
Department of Neurosurgery,Changshu NO.2 People's Hospital,Changshu 215500,China
关键词:
神经内镜垂体腺瘤假包膜
Keywords:
neuroendoscopypituitary adenomapseudocapsule
分类号:
R736.4
文献标志码:
D
摘要:
目的 探讨神经内镜下切除的垂体腺瘤假包膜的病理学表现和手术效果,以及切除垂体腺瘤假包膜的必要性。方法 将38例垂体腺瘤患者分为神经内镜手术组和显微镜手术组。神经内镜手术组术中行假包膜切除;显微镜手术组因观察不到,不行假包膜切除。术后对假包膜进行病理检查,观察假包膜内是否存在垂体腺瘤组织。对两组患者术后3个月的残留复发率和血垂体功能激素水平进行比较。结果 病理检查示垂体腺瘤假包膜中存在肿瘤组织。神经内镜手术组术后3个月的残留复发率(11.1%)明显低于显微镜手术组(45.0%),垂体功能激素水平正常率(66.7%)明显高于显微镜手术组(30.8%)。结论 垂体腺瘤假包膜中存在垂体腺瘤组织,神经内镜下可以实现假包膜切除,切除假包膜可降低垂体腺瘤的残留复发率。
Abstract:
Objective To provide a clinical reference for the necessity of surgical removal of pseudocapsule of pituitary adenoma through the pathological study of pseudocapsule and clinical data analysis of pituitary adenoma resected by neuroendoscopy.Methods 38 patients were divided into the neuroendoscopic operation group and the microscope operation group.The pseudocapsule was excised in neuroendoscopic operation group.The microscope operation group did not excise pseudocapsule.Then a pathological examination of the pseudocapsule was taken to confirm whether there was pituitary adenoma tissue in the pseudocapsule.It was compared in two groups that the residual recurrence rate and functional hormone change after three months.Results There were tumor tissue in pseudocapsule of pituitary adenoma.The residual recurrence rate of neuroendoscopic operation group(11.1%) was significantly lower than that of the microscope group(45.0%) after 3 months.Functional pituitary adenoma:The normal rate of functional hormone in microscope operation group (30.8%) is lower than that in the neuroendoscopic operation group (66.7%).Conclusions There was pituitary adenoma tissue in the pseudocapsule of pituitary adenoma.By the neuroendoscopy,the pseudocapsule of pituitary adenoma can be removed.The removal of pseudocapsule can reduce the residual recurrence rate of pituitary adenoma.

相似文献/References:

[1]佘磊,李育平,张恒柱,等.神经内镜锁孔入路与传统开颅术治疗颅内血肿的对比研究[J].临床神经外科杂志,2014,(01):33.
[2]徐成伟,朱宏伟,高乃康,等.142例鞍区占位病变手术治疗总结[J].临床神经外科杂志,2014,(01):51.
[3]马俊伟,蒋栋毅,陈寒春,等.神经内镜下经鼻蝶入路垂体腺瘤手术切除的临床疗效分析[J].临床神经外科杂志,2015,(01):48.
[4]荣道建,杨晓健,赵俊伟.神经内镜辅助原发性三叉神经显微血管减压术[J].临床神经外科杂志,2015,(02):89.
[5]王勇,吴冲,张洪亮,等.神经内镜下切除功能性垂体瘤术后激素水平改善的效果分析[J].临床神经外科杂志,2015,(04):265.
[6]李强,许琼冠,刘达远,等.缺氧诱导因子-1α、血管内皮细胞生长因子在垂体腺瘤中的表达及其意义[J].临床神经外科杂志,2015,(05):363.
[7]张元隆,江常震,王晨阳.经额开颅手术后额窦炎的处理[J].临床神经外科杂志,2015,(05):380.
[8]耿鑫.CT引导内窥镜立体定向术治疗颅内病变的临床研究[J].临床神经外科杂志,2014,(02):122.
[9]陈旭东,朱美晓,成力伟,等.微骨孔入路神经内镜下超早期治疗脑出血疗效研究[J].临床神经外科杂志,2014,(03):197.
[10]段海锋,范月超.转录因子YY1对垂体瘤侵袭性的影响[J].临床神经外科杂志,2014,(06):416.
[11]张红波,陈谦学,穆林森.斜坡异位泌乳素垂体腺瘤1例临床分析并文献复习[J].临床神经外科杂志,2016,(01):16.

更新日期/Last Update: 1900-01-01