[1]刘海兵,魏梁锋,洪景芳,等.创伤性重型颅脑损伤早期格拉斯哥昏迷量表评分动态变化与CTP的相关性[J].临床神经外科杂志,2018,15(06):448-451.[doi:10.3969/j.issn.1672-7770.2018.06.012]
 LIU Hai-bing,WEI Liang-feng,HONG Jing-fang,et al.The correlation analysis between the dynamic change of the early Glasgow coma scale and computer tomography perfusion imaging in severe traumatic brain injury[J].Journal of Clinical Neurosurgery,2018,15(06):448-451.[doi:10.3969/j.issn.1672-7770.2018.06.012]
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创伤性重型颅脑损伤早期格拉斯哥昏迷量表评分动态变化与CTP的相关性()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
15
期数:
2018年06期
页码:
448-451
栏目:
论著
出版日期:
2018-12-15

文章信息/Info

Title:
The correlation analysis between the dynamic change of the early Glasgow coma scale and computer tomography perfusion imaging in severe traumatic brain injury
作者:
刘海兵魏梁锋洪景芳黄艺生高进喜曾炳香池彬曾磊王守森
350025 福州,解放军第900医院神经外科(刘海兵,魏梁锋,洪景芳,高进喜,曾炳香,池彬,王守森),放射科(黄艺生,曾磊)
Author(s):
LIU Hai-bingWEI Liang-fengHONG Jing-fanget al.
Department of Neurosurgery,PLA 900 Hospital,Fuzhou 350025,China
关键词:
重型颅脑损伤格拉斯哥昏迷量表评分CT灌注成像血流动力学
Keywords:
severe traumatic brain injuryGlasgow coma scaleCT prefusion imaginghemodynamic
分类号:
R651.1
DOI:
10.3969/j.issn.1672-7770.2018.06.012
文献标志码:
A
摘要:
【摘要】目的通过CT灌注成像(CTP)观察创伤性重型颅脑损伤患者血流动力学的变化;探讨创伤性重型颅脑损伤早期格拉斯哥昏迷量表(Glasgow coma scale,GCS)评分变化与CTP的相关性。方法动态评定20例创伤性重型颅脑损伤患者GCS评分,行CT检查明确重型颅脑损伤诊断;并分别在外伤后或术后第2 d、7 d 及14 d行CTP检查。分析创伤性重型颅脑损伤早期GCS评分与脑局部脑血流量(region cerebral blood flow,rCBF)、局部脑血容量(region cerebral blood volume,rCBV)及血液通过组织的平均通过时间(mean transit time,MTT)之间的关系。结果创伤性重型颅脑损伤患者早期GCS评分与CBF、CBV呈正相关,与MTT呈负相关。表明患者伤后GCS评分越高,脑组织缺血的程度越低。结论CTP技术有助于了解颅脑损伤后局部脑组织血流灌注状况,rCBF、rCBV和MTT与创伤性重型颅脑损伤早期GCS评分存在相关性。
Abstract:
Abstract:ObjectivesTo probe into the the correlation between the change of the early Glasgow coma scale (GCS) and computer tomography perfusion (CTP),via CTP technology understand the change of hemodynamics in severe traumatic brain injury(sTBI) patients.Methods 20 patients with sTBI were included in this study.The dynamic GCS scores were recorded and the data of rCBF,rCBV and MTT were detected by CTP at after the injury and at 2,7,and 14 days after surgery.The relations between the dynamic change of early GCS scores and the data of rCBF,rCBV and MTT were analyzed by using statistical methods.ResultsIt was found that there is a positive correlation between the early GCS scores and rCBF and rCBV in sTBI patients,however the early GCS scores negatively correlated with MTT.This meaned that a high GCS scores after injury indicated a low degree of cerebral ischemia.ConclusinsCTP imaging is helpful to understand the blood perfusion in local cerebral tissues after injury.rCBF and MTT are significantly corrected with the early GCS in severe traumatic brain injury patients.

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更新日期/Last Update: 1900-01-01