[1]闫天芳,刘钊,刘攀,等.3D1H-MRS多模态成像技术辅助下扩大胶质瘤手术切除范围的研究[J].临床神经外科杂志,2018,15(06):452-456.[doi:10.3969/j.issn.1672-7770.2018.06.013]
 YAN Tian-fang,LIU Zhao,LIU Pan,et al.Reaserch on enlarged surgical resection range of glioma with assistant of 3D1H-MRS multimodal imaging[J].Journal of Clinical Neurosurgery,2018,15(06):452-456.[doi:10.3969/j.issn.1672-7770.2018.06.013]
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3D1H-MRS多模态成像技术辅助下扩大胶质瘤手术切除范围的研究()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
15
期数:
2018年06期
页码:
452-456
栏目:
论著
出版日期:
2018-12-15

文章信息/Info

Title:
Reaserch on enlarged surgical resection range of glioma with assistant of 3D1H-MRS multimodal imaging
作者:
闫天芳刘钊刘攀徐建堃林庆堂徐庚
100053 北京,首都医科大学宣武医院神经外科(闫天芳,刘攀,徐建堃,林庆堂,徐庚);首都医科大学三博脑科医院神经外科(刘钊)
Author(s):
YAN Tian-fangLIU ZhaoLIU Panet al.
Department of Neurosurgery,Xuanwu Hospital,Capital Medical University,Beijing 100053,China
关键词:
3D1H-MRS胶质瘤手术治疗多模态影像系统
Keywords:
3D1H-MRSgliomasurgical resectionmultimodal imaging system
分类号:
R651.1;739.41
DOI:
10.3969/j.issn.1672-7770.2018.06.013
文献标志码:
A
摘要:
【摘要】目的根据术前CHO/NAA指数(CNI)值及普通MRI判断胶质瘤切除范围对肿瘤近全切除率的影响,明确3D1H-MRS多模态成像对扩大胶质瘤手术切除范围的作用。方法将40例胶质瘤患者随机分为传统手术组与CNI手术组,术前所有患者均接受3D1H-MRS及相关多模态影像学检查。CNI手术组根据MRS影像中CNI>1的范围进行手术切除。传统手术组根据普通MRI检查结果确定切除范围。术后1周内分别复查MRI平扫加增强及3D1H-MRS,并分别计算两者的近全切除率(gross total resection rate,GTRR)与CNI-GTRR。记录患者术后1周KPS评分。结果根据普通MRI计算的肿瘤近全切除率,两组数据间无明显差异,传统手术组为85%,CNI手术组为90%。根据3D1H-MRS影像CNI值计算的近全切率,CNI手术组(60%)较传统手术组(30%)更高。尤其在高级别胶质瘤中,3D1H-MRS辅助手术对提高近全切率的作用(70%)较传统手术组(12.5%)更为明显。两组患者的术后1周平均KPS评分结果相近。结论3D1H-MRS辅助下胶质瘤手术对肿瘤浸润区的切除范围更大。
Abstract:
Abstract:ObjectiveTo explore the application of multimodal imaging system with 3D1H-MRS on the extent of glioma resection,according to the effects of preoperative CNI value and conventional MRI on the gross total removal rates.Methods40 patients with gliomas were randomly divided into conventional surgery group(CSG) and CNI surgery group(CNI-SG).All of the patients accepted 3D1H-MRS and relative multimodal image scans.For CNI-SG,the resection scope was based on the value CHO/NAA(CNI)>1 according to MRS imaging.For CSG,the scope was confirmed according to conventional MRI.All the patients accepted conventional MRI and 3D1H-MRS 1 week postoperatively,and the gross total removal rates based on the conventional MRI and MRS imaging were gained respectively.Postoperative KPS was also recorded.ResultsAccording to postoperative MRI,there was no obvious statistical difference of the gross tumor removal rates between the CSG(85%) and CNI-SG(90%).According to CNI value,the gross tumor removal rate of CNI-CSG(60%) was higher than CSG(30%).Especially for high grade gliomas,3D1H-MRS assisted surgery(CNI-CSG) exerted a higher CNI-GTRR than CSG.There was no obvious difference of postoperative KPS between the two groups.ConclusionSurgical resection range of glioma can be enlarged with assistant of the application of 3D1H-MRS multimodal imaging.

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更新日期/Last Update: 1900-01-01