[1]付强,李绍山,魏康康,等.“脑室型”胼胝体胶质瘤的手术治疗[J].临床神经外科杂志,2019,16(1):17-28.[doi:10.3969/j.issn.1672-7770.2019.01.004]
 FU Qiang,LI Shao-shan,WEI Kang-kang,et al.Microsurgical treatment of “intraventricular type” corpus callosum glioma[J].Journal of Clinical Neurosurgery,2019,16(1):17-28.[doi:10.3969/j.issn.1672-7770.2019.01.004]
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“脑室型”胼胝体胶质瘤的手术治疗()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
16
期数:
2019年第1期
页码:
17-28
栏目:
胶质瘤专题
出版日期:
2019-02-18

文章信息/Info

Title:
Microsurgical treatment of “intraventricular type” corpus callosum glioma
作者:
付强李绍山魏康康刘波周庆九
830054 乌鲁木齐,新疆医科大学第一附属医院神经外科
Author(s):
FU Qiang LI Shao-shan WEI Kang-kang et al.
Department of Neurosurgery, The First Teaching Hospital of Xinjiang Medical University, Wulumuqi 830054, China
关键词:
“脑室型”胼胝体胶质瘤显微外科手术
Keywords:
“intraventricular type” corpus callosum glioma microsurgery treatment
分类号:
R739.41;R651
DOI:
10.3969/j.issn.1672-7770.2019.01.004
文献标志码:
A
摘要:
目的探讨“脑室型”胼胝体胶质瘤的手术治疗效果。方法回顾性分析新疆医科大学第一附属医院神经外科自2015年1月—2018年1月手术,并经病理检查证实的12例“脑室型”胼胝体胶质瘤患者的临床资料、显微外科手术方式及病理结果;评价患者的肿瘤切除程度及术后临床效果。采用电话、门诊等方式对患者进行随访。结果肿瘤次全切除患者9例,大部分切除者3例。术后病理检查示,9例患者为胶质母细胞瘤(WHO Ⅳ级),2例患者为弥漫性星形细胞瘤(WHO Ⅱ级),1例患者为间变型星形细胞瘤(WHO Ⅲ级)。术后,颅高压症状改善者7例,言语障碍改善者1例,认知功能障碍改善1例,大小便失禁改善2例。术后KPS评分>60分者7例,<60分者5例。随访3个月—3年,2例患者存活,其余患者均死亡。结论“脑室型”胼胝体胶质瘤多合并颅内压增高症状、认知功能障碍、梗阻性脑积水;肿瘤侵犯结构广泛,手术部位深、难度大、风险高,肿瘤难以全切;病理类型多为胶质母细胞瘤,预后差。显微外科手术治疗的近期效果较好,能有效缓解颅内高压症状,提高患者的生存质量。
Abstract:
Abstract:ObjectiveTo investigate the microsurgical effect of “intraventricular type” corpus callosum glioma. MethodsThe clinical data, microsurgical treatment and pathological results of 12 cases of “Intraventricular type” corpus callosum gliomas treated in the First Teaching Hospital of Xinjiang Medical University from January 2015 to January 2018 were analyzed retrospectively. The degree of tumor resection and the postoperative clinical performance were evaluated. The followup was carried out by telephone and outpatient clinic. Results9 cases received subtotal resection and 3 received partial resection. 9 were glioblastoma WHO Ⅳ grade,2 were diffused astrocytoma WHO Ⅱ grade and 1 was anaplastic astrocytoma WHO Ⅲ grade. Postoperative symptoms of cranial hypertension improved in 7 cases,speech disorder improved in 1, cognitive impairment improved in 1 case and gatism improved in 2 cases. 7 cases of postoperative KPS score was>60 and 5 cases was<60. The follow-up from 3 months to 3 years showed 2 cases survived and the others all died. Conclusions “Intraventricular type” corpus callosum glioma usually combines with intracranial hypertension, cognitive dysfunction and obstructive hydrocephalus. The operation is difficult and risky because of its deep position and extensive invasion. The tumor seldom receives total resection. Most of them are glioblastoma,this histopathology result doomed to poor prognosis. The shortterm effect of microsurgical treatment for “intraventricular type” corpus callosum glioma is better. It can effectively relieve the symptoms of intracranial hypertension and improve the quality of life of patients.

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更新日期/Last Update: 2019-02-18