[1]李云林,谭泊静,秦广彪,等.多形性黄色瘤型星形细胞瘤与癫痫1例报告并文献复习[J].临床神经外科杂志,2019,16(2):165-168.[doi:10.3969/j.issn.1672-7770.2019.02.014]
 LI Yun-lin,TAN Bo-jing,QIN Guang-biao,et al.Pleomorphic xanthoastrocytoma and epilepsy(a report of one case and review of literature)[J].Journal of Clinical Neurosurgery,2019,16(2):165-168.[doi:10.3969/j.issn.1672-7770.2019.02.014]
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多形性黄色瘤型星形细胞瘤与癫痫1例报告并文献复习()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
16
期数:
2019年第2期
页码:
165-168
栏目:
论著
出版日期:
2019-04-17

文章信息/Info

Title:
Pleomorphic xanthoastrocytoma and epilepsy(a report of one case and review of literature)
作者:
李云林谭泊静秦广彪马康平易林华高志杰姬辛那
100020北京,首都儿科研究所附属儿童医院神经外科(李云林,谭泊静,秦广彪,马康平,易林华),神经内科(高志杰,姬辛那)
Author(s):
LI Yun-lin TAN Bo-jing QIN Guang-biao et al.
Department of Neurosurgery, Children's Hospital Affiliated to Capital Institute of Pediatrics, Beijing 100020, China
关键词:
多形性黄色瘤型星形细胞瘤癫痫皮质脑电图监测
Keywords:
pleomorphic xanthoastrocytomaepilepsyelectrocorticography
分类号:
R742.1;R739.41
DOI:
10.3969/j.issn.1672-7770.2019.02.014
文献标志码:
A
摘要:
【摘要】目的 探讨实质型多形性黄色瘤型星形细胞瘤(PXA)的临床、影像学表现、病理学特点及致痫机制和外科治疗方案。方法回顾性分析1例PXA患儿的临床资料。结果患儿男,10岁,临床表现为反复癫痫发作。脑电图示右颞区为主的慢波、棘慢波发放,头颅MRI平扫见右颞中部皮质结构异常,增强扫描局部呈不均匀片状强化。术中见病变位于右侧颞中回后部,局部皮质略肿胀、颜色稍黄、质地偏韧、边界欠清,自皮质表面向深部生长。术中皮质脑电图(ECoG)监测见癫痫放电主要位于病变及其周围皮质,扩大切除病变后再次监测未见异常癫痫波发放。术后随访9个月无癫痫发作。结论PXA是一种少见的中枢神经系统肿瘤,多以癫痫发作为首发症状。在ECoG监测下行病变扩大切除是治疗PXA的有效方法。
Abstract:
Abstract: ObjectiveTo investigate the imaging features, pathological characteristics, epileptogenic mechanism and surgical treatment of pleomorphic xanthoastrocytoma(PXA). MethodsThe clinical data of 1 patient with PXA were analyzed retrospectively. ResultsA 10-year-old boy presented with repeated epileptic seizures as his first clinical manifestation,whose EEG monitoring showed abnormal discharges like slow and spike-slow waves mainly in the right temporal lobe regions. MRI scan showed a small lesion located in the right middle and posterior part of temporal lobe with no specific distinct patterns on T1 and T2-weighted imaging, and heterogeneous patchy enhancement could be found in the lesion. During the operation, the lesion was found in the posterior part of the middle temporal gyrus, which was slightly swollen, yellowish in color, tough in texture and unclear in border, and grew from the cortical surface to the deep part. Intraoperative electrocorticography(ECoG) monitoring revealed that epileptic discharges were mainly located in and around the lesion. No abnormal epileptic discharges showed after extended resection of the lesion. No seizures occurred at 9 months followed up. ConclusionsPXA is a rare central nervous system neoplasm, which can cause seizures frequently. Extended resection of the lesion under ECoG monitoring can effectively treat the lesion and seizure.

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更新日期/Last Update: 2019-04-17