[1]李倩,谢琛,刘静茹,等.中国大陆人群脑卒中后癫痫发生率的Meta分析[J].临床神经外科杂志,2019,16(4):308-313.[doi:10.3969/j.issn.1672-7770.2019.04.007]
 LI Qian,XIE Chen,LIU Jing-ru,et al.Meta-analysis of incidence of post-stroke epilepsy in Chinese population[J].Journal of Clinical Neurosurgery,2019,16(4):308-313.[doi:10.3969/j.issn.1672-7770.2019.04.007]
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中国大陆人群脑卒中后癫痫发生率的Meta分析()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
16
期数:
2019年第4期
页码:
308-313
栏目:
癫痫专题
出版日期:
2019-08-15

文章信息/Info

Title:
Meta-analysis of incidence of post-stroke epilepsy in Chinese population
作者:
李倩谢琛刘静茹韩红侯丽敏赵志芳
054001 邢台,邢台市第一医院神经内科
Author(s):
LI Qian XIE Chen LIU Jing-ru et al.
Department of Neurology, Xingtai City First Hospital, Xingtai 054001, China
关键词:
脑卒中癫痫发生率Meta分析
Keywords:
strokeepilepsyincidenceMeta-analysis
分类号:
R742.1
DOI:
10.3969/j.issn.1672-7770.2019.04.007
文献标志码:
A
摘要:
【摘要】目的 研究中国大陆地区脑卒中患者脑卒中后癫痫的发生率。方法通过知网、万方、维普、PubMed、EMbase、Wiley等中英文数据库,查阅2010年1月—2018年6月关于中国大陆地区脑卒中后癫痫发生率的研究报道。对纳入文献进行质量评价,使用Stata 11.0软件对收集的数据进行Meta分析。结果共纳入36篇文献,共计50 748例脑卒中患者,其中脑卒中后发生癫痫的患者3 913例,脑卒中后癫痫的发生率为7.5%(95 CI 6.8%~8.2%)。亚组分析显示,脑卒中后早发型癫痫的发生率(4.7% )明显高于迟发型癫痫(2.7%);男性脑卒中后癫痫发生率(7.8%)高于女性(7.3%);差异均有统计学意义(均P<0.01)。脑梗死、脑出血、蛛网膜下腔出血后癫痫的发生率分别为6.2%、9.0%、15.5%,差异有统计学意义(P<0.01)。结论脑卒中后癫痫发生率与患者的性别和卒中类型有关;男性、脑出血可能是脑卒中后癫痫发生的危险因素。
Abstract:
Abstract: ObjectiveTo evaluate the incidence of post-stroke epilepsy in Chinese population by Meta-analysis. MethodsThe CNKI, Wanfang, Chongqing VIP network, PubMed, EMbase and Wiley database were searched to identify observational studies of post-stroke seizures from January 2010 to June 2018. The data were analyzed by Meta-analysis with Stata 11.0 software. Results36 articles involving 50 748 stroke patients and 3 913 post-stroke epilepsy patients were included. Meta-analysis showed the incidence of post-stroke epilepsy was 7.5% (95% CI:6.8%-8.2%). Subgroup analysis showed that the incidence of early post-stroke epilepsy was higher than that of late epilepsy (4.7% vs 2.7%, P<0.01). The incidence of male post-stroke epilepsy was slightly higher than that of female (7.8% vs 7.3%, P<0.01). The incidence of epilepsy after cerebral infarction, cerebral hemorrhage and subarachnoid hemorrhage were 6.2%, 9.0% and 15.5% respectively(P<0.01). ConclusionsThe incidence of post-stroke epilepsy in Chinese is 7.5%. The incidence of post-stroke epilepsy is related to gender and stroke type. Male and cerebral hemorrhage may be the risk factors of post-stroke epilepsy.

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更新日期/Last Update: 2019-08-01