[1]李士强,尚爱加,陶本章,等.侵及马尾神经的原发性神经淋巴瘤病1例报告及文献复习[J].临床神经外科杂志,2020,17(04):442-444.[doi:DOI:10.3969/j.issn.1672-7770.2020.04.018]
 LI Shi-qiang,SHANG Ai-jia,TAO Ben-zhang,et al.Primary neurolymphomatosis of the cauda equina(report of one case and review of literature)[J].Journal of Clinical Neurosurgery,2020,17(04):442-444.[doi:DOI:10.3969/j.issn.1672-7770.2020.04.018]
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侵及马尾神经的原发性神经淋巴瘤病1例报告及文献复习()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
17
期数:
2020年04期
页码:
442-444
栏目:
临床研究
出版日期:
2020-08-14

文章信息/Info

Title:
Primary neurolymphomatosis of the cauda equina(report of one case and review of literature)
文章编号:
202004018
作者:
李士强尚爱加陶本章白少聪高干
100853 北京,解放军总医院第一医学中心神经外科(李士强,尚爱加,陶本章,白少聪,高干);解放军第八十集团军医院神经外科(李士强)
Author(s):
LI Shi-qiang SHANG Ai-jia TAO Ben-zhang et al.
Department of Neurosurgery, The Seventh Medical Center of PLA General Hospital, Beijing 100853, China
关键词:
马尾神经神经淋巴瘤病甲氨蝶呤组织活检
Keywords:
cauda equina neurolymphomatosis methotrexate biopsy
分类号:
R739.41
DOI:
DOI:10.3969/j.issn.1672-7770.2020.04.018
文献标志码:
B
摘要:
目的探讨原发性神经淋巴瘤病(NL)的临床特征、诊断要点及治疗方法。方法回顾性分析1例侵及马尾神经的原发性神经淋巴瘤病患者的临床资料;结合患者的临床表现、影像学特征、病理学检查结果,对相关文献进行总结复习。结果本例患者为侵及马尾神经的原发性神经淋巴瘤病,主要表现为马尾综合征;通过组织活检明确诊断,病理诊断为弥漫大B细胞淋巴瘤(WHO Ⅳ级)。结论原发性神经淋巴瘤病临床罕见,早期诊断困难。当怀疑是此病时,应尽早进行组织活检;大剂量静脉注射甲氨蝶呤是目前首选的治疗方法。
Abstract:
To explore the clinical features, diagnosis and treatment of primary neurolymphomatosis(NL). Methods The clinical data of one patient with primary NL of the cauda equina were analyzed retrospectively. Combined with clinical manifestations, imaging features and pathological examination results, the relevant literature were summarized and reviewed. Results The patient was diagnosed as primary NL of the cauda equina by biopsy and pathologic diagnosis confirmed diffuse large B-cell lymphoma(WHO Grade Ⅳ). Conclusions Primary NL is rare and difficult to diagnose in its early stages. When NL is highly suspected, biopsy should be performed as soon as possible. High-dose intravenous methotrexate is the first choice at present.
更新日期/Last Update: 2020-08-18