[1]赵甦,李巧玉,孙而艺.铁死亡在神经系统肿瘤中的作用及其机制研究进展[J].临床神经外科杂志,2021,18(01):110-116.[doi:DOI:10.3969/j.issn.1672-7770.2021.01.025]
 ZHAO Su,LI Qiao-yu,SUN Er-yi..Recent progress of ferroptosis in nervous system tumor[J].Journal of Clinical Neurosurgery,2021,18(01):110-116.[doi:DOI:10.3969/j.issn.1672-7770.2021.01.025]
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铁死亡在神经系统肿瘤中的作用及其机制研究进展()
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《临床神经外科杂志》[ISSN:1672-7770/CN:32-1727/R]

卷:
18
期数:
2021年01期
页码:
110-116
栏目:
综述
出版日期:
2021-02-15

文章信息/Info

Title:
Recent progress of ferroptosis in nervous system tumor
文章编号:
202101025
作者:
赵甦李巧玉孙而艺
212002 镇江,江苏大学附属人民医院神经外科
Author(s):
ZHAO Su LI Qiao-yuSUN Er-yi.
Department of Neurosurgery, Peoples Hospital Affiliated to Jiangsu University, Zhenjiang 212002, China
关键词:
ferroptosis nervous system tumor regulator
Keywords:
ferroptosis nervous system tumor regulator
分类号:
R739.41
DOI:
DOI:10.3969/j.issn.1672-7770.2021.01.025
文献标志码:
A
摘要:
Ferroptosis is a newly proposed cell death mode in recent years, which is different from the traditional cell death mode, apoptosis, cell necrosis and autophagy. Its molecular characteristics include iron-dependent accumulation of lipid reactive oxygen species(ROS), mitochondrial morphological changes and damage to membrane permeability. In the nervous system, studies have found that it plays an important role in neurodegenerative diseases such as Parkinson’s disease(PD) and Alzheimer’s disease(AD). With the further study on ferroptosis, it has been revealed that ferroptosis plays an important role in ischemic and hemorrhagic stroke and nervous system tumors. At present, the reviews on this aspect in China are relatively few. In this paper, the research progress in the mechanism of ferroptosis in nervous system tumors will be reviewed.
Abstract:
Ferroptosis is a newly proposed cell death mode in recent years, which is different from the traditional cell death mode, apoptosis, cell necrosis and autophagy. Its molecular characteristics include iron-dependent accumulation of lipid reactive oxygen species(ROS), mitochondrial morphological changes and damage to membrane permeability. In the nervous system, studies have found that it plays an important role in neurodegenerative diseases such as Parkinson’s disease(PD) and Alzheimer’s disease(AD). With the further study on ferroptosis, it has been revealed that ferroptosis plays an important role in ischemic and hemorrhagic stroke and nervous system tumors. At present, the reviews on this aspect in China are relatively few. In this paper, the research progress in the mechanism of ferroptosis in nervous system tumors will be reviewed.
更新日期/Last Update: 2021-02-20